Acne Inflammation
"Conclusions: This study demonstrates that 5% sodium L-ascorbyl-2-phosphate is efficacious as monotherapy for the treatment of acne. APS 5% lotion offers a novel addition to our current acne armamentarium."
Woolery-Lloyd, Heather et al. “Sodium L-ascorbyl-2-phosphate 5% lotion for the treatment of acne vulgaris: a randomized, double-blind, controlled trial.” Journal of cosmetic dermatology vol. 9,1 (2010): 22-7. doi:10.1111/j.1473-2165.2010.00480.x
In a smaller, 8-week study in 30 people, those who used 5% SAP had a 48.8% reduction in acne lesions. What’s more, those who used a combination of SAP and 2% retinol — a vitamin A derivative — had a 63.1% reduction
Ruamrak, C et al. “Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment.” International journal of cosmetic science vol. 31,1 (2009): 41-6. doi:10.1111/j.1468-2494.2008.00479.x (edited)